Anyone shopping this ingredient should start with the label math, because berberine listings vary widely in milligrams per capsule and in how many capsules make a serving.
- Compare milligrams per capsule against milligrams per serving, since a 500 mg capsule may be a two-capsule dose.
- Look for the extract source and standardization, such as berberine HCl from Berberis aristata root.
- Check capsule shell type and third-party testing statements if you avoid gelatin or want purity documentation.
Berberine interacts with some prescriptions, so talk with your own clinician before adding it to a routine.