Invasion contains 350 black-bordered cards (110 rare, 110 uncommon, 110 common, and 20 basic lands). Invasion's expansion symbol is the symbol of the coalition, a cooperative effort of Dominarian forces from all five colors banded together to oppose Yawgmoth and the Phyrexians.

The set featured some legendary cards of the Weatherlight's crew: Captain Sisay and Hanna, Ship's Navigator. It also introduced the kavu. The set was accompanied by the novel of the same name.