Ergonomic Mice

Ergonomic mice for computer users seeking wrist comfort and precision control.

Featured brands

Authenticated productsVerified shops

Logitech

Free shipping

2.4G Wireless Vertical Mouse, Rechargeable Ergonomic Optical Mice: 3 Adjustable DPI 800/1200/1600 Levels 6 Buttons, for Laptop, PC, Computer, Desktop, Notebook etc, White

4.8

46 sold

$20.99

Free shipping

Meetion Ergonomic Vertical Wireless Mouse (Right-Hand) - Tri-Mode Bluetooth & 2.4G, USB-C Rechargeable Multi-Device Mouse for Mac/PC

3 sold

-50%$17.99$35.98

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Logitech

Logitech MX Master 4 Contour Ergonomic Anti-Slip Cable-Free Haptic Clicky Mouse - Advanced Performance Haptic Feedback, Ultra-Fast Scrolling, USB-C Charging, Bluetooth, Windows, MacOS - Black

4.3

725 sold

$155.99

Free shipping

JOMAA Dual-Mode Vertical Ergonomic Computer Mouse, Dual Wireless 5.1 BT & 2.4G Adapter, 500 mAh Rechargeable, Adjustable DPI with 2400 DPI Max, Silent Click, Intelligent Power Saving, LED Display Screen, Side Buttons, Win/IOS/Android Office Accessory

4.8

114 sold

-58%$31.50$75.00

Free shipping

SABLUTE MAM51 Ergonomic Vertical Mouse - Wireless Bluetooth, 4000 DPI, 8 Buttons, Side Scrolling Wheel, for Small-Medium Hands, PC/Desktop Office Use

3.0

14 sold

-35%$23.99$36.99

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SABLUTE MAM2 Lightweight Ergonomic Rechargeable Wireless Trackball Mouse with Thumb Controls, 5-Level DPI Switch, 2.4G USB & Bluetooth 3-Device Connectivity, Built-In 500mAh Li-Ion Cells, Mouse for Computer (Office Workers’ PC, Laptop)

5.0

69 sold

$36.99

Free shipping

SABLUTE MAM51 59° Vertical Ergonomic Mouse, Bluetooth & 2.4G Wireless, 8 Multi-Buttons, Adjustable 4000 DPI, Side Scroll Wheel, Relieves Wrist Pressure, for Office Users, Small-Medium Hands, PC/Tablet, Lifetime Support

5.0

6 sold

Limited time deal

-38%$22.99$36.99

Free shipping

JOMAA v530 USB-C Charging Port Wireless Vertical Ergonomic Computer Mouse - 2.4G-Bluetooth Dual-Mode, 4000 DPI, 9 Buttons, RGB Backlit LED Lights, Silent Clicks, 600 mAh Battery, High Precision, Computer Peripherals for Laptops/PC Users

5.0

5 sold

-50%$32.50$65.00

UGREEN Compact Right-Handed Wireless Computer Mouse - Bluetooth 5.0+2.4G Ergonomic 5-Button Office Accessory with Adjustable DPI (1000/1600/2000/3200/4000), Mouse Arm Prevention, Compatible with PC/Laptop/Tablet (Small Size)

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UGREEN.US

UGREEN Compact Right-Handed Wireless Computer Mouse - Bluetooth 5.0+2.4G Ergonomic 5-Button Office Accessory with Adjustable DPI (1000/1600/2000/3200/4000), Mouse Arm Prevention, Compatible with PC/Laptop/Tablet (Small Size)

4.8

520 sold

$38.99

Logitech MX Master 4 Wireless Mouse, Advanced Ergonomic Design, MagSpeed Scroll Wheel, Multi-Device & Multi-OS (Bluetooth/USB), USB-C Rechargeable

Free shipping

Newegg, Inc.

Logitech MX Master 4 Wireless Mouse, Advanced Ergonomic Design, MagSpeed Scroll Wheel, Multi-Device & Multi-OS (Bluetooth/USB), USB-C Rechargeable

4.2

64 sold

$165.74

Free shipping

Keychron M5 Wireless Ergonomic Connected Mouse - PC Accessories, 47° Vertical Design, Ultra-Fast 2.4 GHz Connection, Bluetooth and Wired Connection, PixArt 3950 Sensor, 8K Polling Rate, Precise Tracking, Enhanced Control

3.5

51 sold

$69.99

Mute Quiet Mouse Type C Wired Mouse Ergonomic Mini Optical Mause Home Office Mice for Laptop Tablet Windows Android Mac Optical Sensor Mouse Computer Mice

4.9

42 sold

-25%$8.84$11.79

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JOMAA Wireless Ergonomic Vertical Mice 2.4G+Dual-Bluetooth Mouse with OLED Display Silent Click Wireless Rechargeable RGB Backlit Mouse for Desktop/Laptop/PC

$32.90

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ProtoArc EM11 NL Ergonomic Vertical Grip Mouse - Rechargeable Silent Optical Wireless, Mouse Ergonomics, 3 Multi-Device Connectivity, 3-Level Adjustable DPI (1000/1600/2400), 500mAh Battery, Office Accessories, Work Accessories, Gifts Adults

4.7

37.8K sold

Flash sale00:00:00

$28.99

Free shipping

JOMAA Superior Ergonomic Right-Hand Vertical Mouse - 2.4G+5.1 BT Dual Wireless Mode, Rechargeable Silent Click, Adjustable DPI, Multifunction Knob, LED Display Screen, Side Buttons, Smooth & Accurate Tracking, Compatible with Desktops, Laptops

1 sold

$34.00

Free shipping

REDRAGON

Redragon M612 Predator Tactical Wired Optical Gaming Mouse (PC Accessory) - 8000 DPI Adjustable, 11 Programmable Buttons, 5 RGB Backlit Modes, Software-Supported DIY Keybinds, Rapid Fire, Ergonomic Synthetic Rubber, Right-Handed, Teen Boy Gift, Geek Gift

4.7

12.1K sold

-10%$23.39$25.99

Free shipping

TECKNET Wireless Ergonomic Mouse, Rechargeable Wireless Vertical Mouse Rechargeable, 2.4GHz USB Receiver, Silent Click, 6 Adjustable DPI up to 4800, 6 Buttons for Laptop, PC, Optical Tracking, Plug-And-Play

4.6

213 sold

$35.99

Free shipping

JOMAA Ergonomic Small-Hand Mouse Vertical Wireless Bluetooth& 2.4G Mice Wireless Rechargeable, Power Display, 8000 DPI Adjustable, Silent Click, Lightweight Portable Computer Mouse for Desktop/PC

$26.80

Free shipping

JOMAA v530 Ergonomic Vertical Wireless Computer Mouse - Dual Wireless Mode (2.4G/BT 5.1), Silent, 4000 DPI Adjustable, 9 Buttons (Side Buttons), RGB Lights, 600 mAh Rechargeable Work Accessories for Gaming, PC Use

4.3

101 sold

Flash sale00:00:00

-48%$25.14$48.00

UGREEN 2.4G Wireless Vertical Ergonomic Mouse (Bluetooth Not Supported) - 5 Buttons, 4000 DPI, Black & Pink, 176g Computer Peripherals for PC/Laptop PC Accessories, TikTok Shop Fall Deals, Vertical Mouse

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UGREEN.US

UGREEN 2.4G Wireless Vertical Ergonomic Mouse (Bluetooth Not Supported) - 5 Buttons, 4000 DPI, Black & Pink, 176g Computer Peripherals for PC/Laptop PC Accessories, TikTok Shop Fall Deals, Vertical Mouse

4.8

17.1K sold

$24.99

Free shipping

MEETION Ergonomic Vertical Wireless ARGB Mouse for Left Hand - Ambidextrous, 2.4G+Bluetooth 5.2/3.0, Rechargeable, USB-C to A Adapter, 4 Adjustable DPI, High-Quality Materials, Multi-Device for Mac/Windows, Precise Tracking, Promotes Natural Grip

5.0

69 sold

-50%$25.99$51.99

UGREEN Black-Bluetooth 5.0+2.4G Model Dual-Mode Vertical Mouse - Wireless Ergonomic Desk, PC, Work Accessories, 5 Buttons, Adjustable DPI (1000/1600/2000/4000), 176g, AA Battery Required, Compatible with Windows/Mac OS, for Office/Desk Use

Free shipping

UGREEN.US

UGREEN Black-Bluetooth 5.0+2.4G Model Dual-Mode Vertical Mouse - Wireless Ergonomic Desk, PC, Work Accessories, 5 Buttons, Adjustable DPI (1000/1600/2000/4000), 176g, AA Battery Required, Compatible with Windows/Mac OS, for Office/Desk Use

4.6

1.2K sold

$24.99

Free shipping

Compact Ultra-Thin Ergonomic Noiseless Type-C Mouse Jiggler - USB Adapter Compatible, Adjustable Timer, Undetectable Realistic Movement, Driver-Free PC Accessory for Office Users

6 sold

-35%$14.29$21.99

Free shipping

Seenda Ergonomic Connected Mouse MOU-302 - Rechargeable Vertical Wireless Type-C Mouse with USB+Bluetooth, Volume Knob, Quiet Clicks, Adjustable DPI Settings, Non-Slip Control, Multi-Device Compatibility for Windows, Mac OS, Office & Desk Accessories

4.9

1.7K sold

$29.99

Free shipping

REDRAGON

Redragon M908 Wired Ergonomic RGB LED Gaming PC Mouse - 18 Programmable Buttons, Macro Keys, Adjustable, 16.8M Customizable Color Options, PC Accessories, Gaming Setup Accessories for Gamers, Geek Gift

4.8

707 sold

$42.89

Free shipping

ProtoArc EM25 Ergonomic Silent Wireless Computer Mouse - Office Cordless Mouse, 2x Bluetooth, 500mAh Rechargeable Battery, Up to 8000 DPI, Thumb Scroll Wheel, Customizable Buttons, Multi-Device, Windows/Mac/Android Compatible, USB Connectivity

4.8

109 sold

$55.89

Free shipping

ProtoArc EM11 Pro Contoured Ergonomic Wrist Support Wireless Rechargeable Mouse - 6 Programmable Buttons, Side Scroll, 7200 DPI, Multi-Device Bluetooth, for Medium-Large Hands, Windows/Mac/Android (Includes Batteries), Wireless Rechargeable Mice, Right, E

4.7

367 sold

$64.99

Free shipping

MEETION Ergonomic Mouse for Right/Left Hand , Wireless Vertical Mouse RGB Backlit Rechargeable Mice for Bluetooth(5.2 + 3.0) & USB-C to A Adapter 4 Adjustable DPI for Mac/Windows/Andriod/PC/Tablet/iPad

4.8

525 sold

-50%$32.49$64.99

Free shipping

Kysona EM11 Pro Compact Ergonomic Office Cordless Mouse - 55° Handshake Design, OLED Screen, 5-Level 800-6400 DPI, Multi-Device Connectivity, Built-In Rechargeable Li-Ion Battery, Vertical Stand, for Laptop PC, Black White, Wireless Rechargeable Option, W

5.0

6 sold

Limited time deal

-33%$19.99$29.99

Free shipping

SOLAKAKA E9 PRO Ergonomic Vertical Mouse for Office & Productivity, 45° Grip Wireless Mouse with 10 Programmable Side Buttons, Tri-Mode 2.4G/Bluetooth/Wired, PAW3395 36000 DPI, 1000mAh Rechargeable Mouse for PC/Mac - Black

4.2

496 sold

Flash sale00:00:00

$89.89

Introduction

Ergonomic mice reduce wrist strain during long computer sessions. Choose models with contoured shapes, thumb rests, and adjustable DPI settings.

Vertical or contoured grip reduces wrist extension and repetitive strain
Programmable buttons and DPI switches adapt to different tasks
Wireless connectivity and rechargeable batteries support desk mobility

Compare ergonomic mice to find the fit that matches your hand size and workflow.

Ergonomic Mice

Ergonomic mice for computer users seeking wrist comfort and precision control.

Logitech

2.4G Wireless Vertical Mouse, Rechargeable Ergonomic Optical Mice: 3 Adjustable DPI 800/1200/1600 Levels 6 Buttons, for Laptop, PC, Computer, Desktop, Notebook etc, White

Meetion Ergonomic Vertical Wireless Mouse (Right-Hand) - Tri-Mode Bluetooth & 2.4G, USB-C Rechargeable Multi-Device Mouse for Mac/PC

Logitech MX Master 4 Contour Ergonomic Anti-Slip Cable-Free Haptic Clicky Mouse - Advanced Performance Haptic Feedback, Ultra-Fast Scrolling, USB-C Charging, Bluetooth, Windows, MacOS - Black

JOMAA Dual-Mode Vertical Ergonomic Computer Mouse, Dual Wireless 5.1 BT & 2.4G Adapter, 500 mAh Rechargeable, Adjustable DPI with 2400 DPI Max, Silent Click, Intelligent Power Saving, LED Display Screen, Side Buttons, Win/IOS/Android Office Accessory

SABLUTE MAM51 Ergonomic Vertical Mouse - Wireless Bluetooth, 4000 DPI, 8 Buttons, Side Scrolling Wheel, for Small-Medium Hands, PC/Desktop Office Use

SABLUTE MAM2 Lightweight Ergonomic Rechargeable Wireless Trackball Mouse with Thumb Controls, 5-Level DPI Switch, 2.4G USB & Bluetooth 3-Device Connectivity, Built-In 500mAh Li-Ion Cells, Mouse for Computer (Office Workers’ PC, Laptop)

SABLUTE MAM51 59° Vertical Ergonomic Mouse, Bluetooth & 2.4G Wireless, 8 Multi-Buttons, Adjustable 4000 DPI, Side Scroll Wheel, Relieves Wrist Pressure, for Office Users, Small-Medium Hands, PC/Tablet, Lifetime Support

JOMAA v530 USB-C Charging Port Wireless Vertical Ergonomic Computer Mouse - 2.4G-Bluetooth Dual-Mode, 4000 DPI, 9 Buttons, RGB Backlit LED Lights, Silent Clicks, 600 mAh Battery, High Precision, Computer Peripherals for Laptops/PC Users

UGREEN Compact Right-Handed Wireless Computer Mouse - Bluetooth 5.0+2.4G Ergonomic 5-Button Office Accessory with Adjustable DPI (1000/1600/2000/3200/4000), Mouse Arm Prevention, Compatible with PC/Laptop/Tablet (Small Size)

Logitech MX Master 4 Wireless Mouse, Advanced Ergonomic Design, MagSpeed Scroll Wheel, Multi-Device & Multi-OS (Bluetooth/USB), USB-C Rechargeable

Keychron M5 Wireless Ergonomic Connected Mouse - PC Accessories, 47° Vertical Design, Ultra-Fast 2.4 GHz Connection, Bluetooth and Wired Connection, PixArt 3950 Sensor, 8K Polling Rate, Precise Tracking, Enhanced Control

Mute Quiet Mouse Type C Wired Mouse Ergonomic Mini Optical Mause Home Office Mice for Laptop Tablet Windows Android Mac Optical Sensor Mouse Computer Mice

JOMAA Wireless Ergonomic Vertical Mice 2.4G+Dual-Bluetooth Mouse with OLED Display Silent Click Wireless Rechargeable RGB Backlit Mouse for Desktop/Laptop/PC

ProtoArc EM11 NL Ergonomic Vertical Grip Mouse - Rechargeable Silent Optical Wireless, Mouse Ergonomics, 3 Multi-Device Connectivity, 3-Level Adjustable DPI (1000/1600/2400), 500mAh Battery, Office Accessories, Work Accessories, Gifts Adults

JOMAA Superior Ergonomic Right-Hand Vertical Mouse - 2.4G+5.1 BT Dual Wireless Mode, Rechargeable Silent Click, Adjustable DPI, Multifunction Knob, LED Display Screen, Side Buttons, Smooth & Accurate Tracking, Compatible with Desktops, Laptops

Redragon M612 Predator Tactical Wired Optical Gaming Mouse (PC Accessory) - 8000 DPI Adjustable, 11 Programmable Buttons, 5 RGB Backlit Modes, Software-Supported DIY Keybinds, Rapid Fire, Ergonomic Synthetic Rubber, Right-Handed, Teen Boy Gift, Geek Gift

TECKNET Wireless Ergonomic Mouse, Rechargeable Wireless Vertical Mouse Rechargeable, 2.4GHz USB Receiver, Silent Click, 6 Adjustable DPI up to 4800, 6 Buttons for Laptop, PC, Optical Tracking, Plug-And-Play

JOMAA Ergonomic Small-Hand Mouse Vertical Wireless Bluetooth& 2.4G Mice Wireless Rechargeable, Power Display, 8000 DPI Adjustable, Silent Click, Lightweight Portable Computer Mouse for Desktop/PC

JOMAA v530 Ergonomic Vertical Wireless Computer Mouse - Dual Wireless Mode (2.4G/BT 5.1), Silent, 4000 DPI Adjustable, 9 Buttons (Side Buttons), RGB Lights, 600 mAh Rechargeable Work Accessories for Gaming, PC Use

UGREEN 2.4G Wireless Vertical Ergonomic Mouse (Bluetooth Not Supported) - 5 Buttons, 4000 DPI, Black & Pink, 176g Computer Peripherals for PC/Laptop PC Accessories, TikTok Shop Fall Deals, Vertical Mouse

MEETION Ergonomic Vertical Wireless ARGB Mouse for Left Hand - Ambidextrous, 2.4G+Bluetooth 5.2/3.0, Rechargeable, USB-C to A Adapter, 4 Adjustable DPI, High-Quality Materials, Multi-Device for Mac/Windows, Precise Tracking, Promotes Natural Grip

UGREEN Black-Bluetooth 5.0+2.4G Model Dual-Mode Vertical Mouse - Wireless Ergonomic Desk, PC, Work Accessories, 5 Buttons, Adjustable DPI (1000/1600/2000/4000), 176g, AA Battery Required, Compatible with Windows/Mac OS, for Office/Desk Use

Compact Ultra-Thin Ergonomic Noiseless Type-C Mouse Jiggler - USB Adapter Compatible, Adjustable Timer, Undetectable Realistic Movement, Driver-Free PC Accessory for Office Users

Seenda Ergonomic Connected Mouse MOU-302 - Rechargeable Vertical Wireless Type-C Mouse with USB+Bluetooth, Volume Knob, Quiet Clicks, Adjustable DPI Settings, Non-Slip Control, Multi-Device Compatibility for Windows, Mac OS, Office & Desk Accessories

Redragon M908 Wired Ergonomic RGB LED Gaming PC Mouse - 18 Programmable Buttons, Macro Keys, Adjustable, 16.8M Customizable Color Options, PC Accessories, Gaming Setup Accessories for Gamers, Geek Gift

ProtoArc EM25 Ergonomic Silent Wireless Computer Mouse - Office Cordless Mouse, 2x Bluetooth, 500mAh Rechargeable Battery, Up to 8000 DPI, Thumb Scroll Wheel, Customizable Buttons, Multi-Device, Windows/Mac/Android Compatible, USB Connectivity

ProtoArc EM11 Pro Contoured Ergonomic Wrist Support Wireless Rechargeable Mouse - 6 Programmable Buttons, Side Scroll, 7200 DPI, Multi-Device Bluetooth, for Medium-Large Hands, Windows/Mac/Android (Includes Batteries), Wireless Rechargeable Mice, Right, E

MEETION Ergonomic Mouse for Right/Left Hand , Wireless Vertical Mouse RGB Backlit Rechargeable Mice for Bluetooth(5.2 + 3.0) & USB-C to A Adapter 4 Adjustable DPI for Mac/Windows/Andriod/PC/Tablet/iPad

Kysona EM11 Pro Compact Ergonomic Office Cordless Mouse - 55° Handshake Design, OLED Screen, 5-Level 800-6400 DPI, Multi-Device Connectivity, Built-In Rechargeable Li-Ion Battery, Vertical Stand, for Laptop PC, Black White, Wireless Rechargeable Option, W

SOLAKAKA E9 PRO Ergonomic Vertical Mouse for Office & Productivity, 45° Grip Wireless Mouse with 10 Programmable Side Buttons, Tri-Mode 2.4G/Bluetooth/Wired, PAW3395 36000 DPI, 1000mAh Rechargeable Mouse for PC/Mac - Black

Introduction

FAQs

They feature a vertical or sculpted shape that keeps the wrist in a neutral position, reducing strain during extended use.

Many include adjustable DPI, low-latency wireless, and programmable buttons, making them viable for both work and casual gaming.

Most work plug-and-play, though optional software unlocks button customization and battery monitoring.

Manufacturers offer small, medium, and large frames; measuring palm length helps select the correct size.

Several brands produce left-handed or ambidextrous models with symmetric or mirrored contours.